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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN5
All Species:
36.97
Human Site:
S299
Identified Species:
73.94
UniProt:
O15484
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15484
NP_004046.2
640
73169
S299
N
G
P
W
S
D
T
S
E
E
W
Q
K
V
S
Chimpanzee
Pan troglodytes
XP_001146965
641
74541
S299
S
G
P
W
S
E
I
S
E
E
W
Q
Q
L
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542293
640
73142
S299
N
G
P
W
S
D
T
S
E
E
W
Q
K
V
S
Cat
Felis silvestris
Mouse
Mus musculus
O08688
640
72936
S299
T
G
P
W
S
D
T
S
E
E
W
Q
K
V
S
Rat
Rattus norvegicus
Q8R4C0
640
73046
S299
T
G
P
W
S
D
T
S
E
E
W
Q
K
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518356
408
46381
E95
G
E
F
W
M
T
F
E
D
V
C
R
Y
F
T
Chicken
Gallus gallus
Q92177
810
93542
S366
N
G
P
W
S
D
K
S
E
E
W
N
F
I
D
Frog
Xenopus laevis
NP_001080808
642
73235
S299
N
G
P
W
S
D
S
S
E
E
W
Q
K
V
S
Zebra Danio
Brachydanio rerio
XP_001345114
642
73723
S299
S
G
P
W
S
D
S
S
E
E
W
K
K
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q11002
828
93944
S343
N
G
P
W
S
D
S
S
P
E
W
R
Y
I
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22036
648
73596
Q309
S
D
D
S
P
E
W
Q
N
V
S
A
S
Q
L
Sea Urchin
Strong. purpuratus
XP_792213
642
72430
S300
N
G
P
W
S
D
G
S
P
E
W
Q
N
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
N.A.
92
N.A.
92.1
90.6
N.A.
51.4
30.8
73.9
71.6
N.A.
30.7
N.A.
40.1
47.6
Protein Similarity:
100
65.5
N.A.
95.6
N.A.
96
94.8
N.A.
57.3
46.9
86.2
83.8
N.A.
45.2
N.A.
57.2
64.9
P-Site Identity:
100
60
N.A.
100
N.A.
93.3
93.3
N.A.
6.6
66.6
93.3
80
N.A.
60
N.A.
0
73.3
P-Site Similarity:
100
93.3
N.A.
100
N.A.
93.3
93.3
N.A.
26.6
73.3
100
100
N.A.
80
N.A.
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
9
9
0
0
75
0
0
9
0
0
0
0
0
9
% D
% Glu:
0
9
0
0
0
17
0
9
67
84
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
9
0
0
0
0
0
9
9
0
% F
% Gly:
9
84
0
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
0
25
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
9
50
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
0
0
0
0
0
9
0
0
9
9
0
0
% N
% Pro:
0
0
84
0
9
0
0
0
17
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
59
9
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% R
% Ser:
25
0
0
9
84
0
25
84
0
0
9
0
9
0
59
% S
% Thr:
17
0
0
0
0
9
34
0
0
0
0
0
0
0
17
% T
% Val:
0
0
0
0
0
0
0
0
0
17
0
0
0
50
0
% V
% Trp:
0
0
0
92
0
0
9
0
0
0
84
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _